{"display":true,"structure":{"allele":{"alpha":{"identifier":"uniprot:P01901","locus":"h2-k","match_type":"histo:exact","name":"H2-Kb","slug":"h2_kb","species_stem":"H2"},"beta":{}},"assemblies":{"1":{"assembly_name":"1r3h_1","chains":["A","B"],"downloaded_at":"2022-11-09T14:31:19.714639"},"2":{"assembly_name":"1r3h_2","chains":["C","D"],"downloaded_at":"2022-11-09T14:31:20.114924"},"3":{"assembly_name":"1r3h_3","chains":["E","F"],"downloaded_at":"2022-11-09T14:31:20.377257"},"4":{"assembly_name":"1r3h_4","chains":["G","H"],"downloaded_at":"2022-11-09T14:31:20.707387"}},"assembly_count":null,"assigned_chains":{"beta2m":{"chains":["B","D","F","H"],"match_type":"histo:assign_chains","score":1.0,"sequence":"IQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM"},"h2-t22":{"chains":["A","C","E","G"],"match_type":"histo:assign_chains","score":0.93,"sequence":"GSHSLRYFYTAVSRPGLGEPWFIIVGYVDDMQVLRFSSKEETPRMAPWLEQEEADDWEQQTHIVTIQGQLSERNLMTLVHFYNKSMDDSHTLQWLQDCDVEPDRHLCLWYNQLAYDSEDLPTLSENPSSCTVGNSTVPQISQHLEGHCSDVLQKYLEKGKERLLRSDPPKAHVTRHPRPEGDVTLRCWALGFYPADITLTWQKDGEELTQDVEFVETRPAGDGTFQKWAAVVVPLGKVQSYTCHVDHEGLPEPLTLRWEP"}},"chronology":{"deposition_date":"2003-10-02","deposition_year":2003,"release_date":"2004-03-30","release_year":2004,"revision_date":"2011-07-13","revision_year":2011},"class":"class_i","classical":false,"complex_type":"h2-t22","components":["h2-t22","beta2m"],"experimental_method":"X-ray diffraction","facets":{},"ligands":[],"locus":"h2-k","manually_edited":{},"missing_residues":[],"page_title":"1R3H | Mouse Non-classical MHC Class I molecule H2-T22","pdb_code":"1r3h","pdb_title":"Crystal structure of t10","peptide":{"actual_sequence":null,"epitope_info":{},"features":[],"full_sequence":null,"gap_info":{},"gapped_sequence":null,"length":{"numeric":null,"text":null},"unnatural_amino_acids":[]},"publication":{"abstract":"T10 is a non-classical class Ib-like major histocompatibility complex (MHC) cell-surface antigen which binds directly to certain gammadelta T-cell receptors in the absence of any exogenous and endogenous ligands, such as peculiar lipids or glycolipids. The crystal structure at 2.5 A resolution of murine T10 was determined by molecular replacement using data from an almost perfectly twinned monoclinic crystal. The space group is P2(1), with unit-cell parameters a = 78.2, b = 70.0, c = 139.2 A, beta = 106.8 degrees. Self-rotation function analysis and various intensity statistics revealed the presence of pseudo-merohedral twinning, but these tests underestimated the true twin fraction of alpha approximately 0.46. Native Patterson analyses pointed to the presence of pseudo-translation among the four molecules present in the asymmetric unit. Data analysis, structure determination and model refinement are discussed.","bibjson":{"author":[{"initials":"MG","lastname":"Rudolph","name":"Rudolph MG"},{"initials":"C","lastname":"Wingren","name":"Wingren C"},{"initials":"MP","lastname":"Crowley","name":"Crowley MP"},{"initials":"YH","lastname":"Chien","name":"Chien YH"},{"initials":"IA","lastname":"Wilson","name":"Wilson IA"}],"identifier":[{"id":"10.1107/s0907444904002239","type":"doi"},{"id":"15039553","type":"pubmed"}],"issue":["Pt 4"],"journal":{"iso_abbreviation":"Acta Crystallogr. D Biol. Crystallogr.","name":""},"pages":["656-64"],"title":"Combined pseudo-merohedral twinning, non-crystallographic symmetry and pseudo-translation in a monoclinic crystal form of the gammadelta T-cell ligand T10.","type":"article","url":"http://scripts.iucr.org/cgi-bin/paper?S0907444904002239","volume":["60"],"year":[2004]},"in_pmc":"N","in_pmce":"N","open_access":"N"},"resolution":"2.50","same_as":{"pdbe":{"url":"https://www.ebi.ac.uk/pdbe/entry/pdb/1r3h"},"rcsb":{"url":"https://www.rcsb.org/structure/1r3h"}},"species":{"common_name":"Mouse","match_type":"histo:assign_species","scientific_name":"Mus musculus","slug":"mus_musculus"},"tcr":null,"title":"Mouse Non-classical MHC Class I molecule H2-T22 at 2.50Å resolution","unique_chain_count":2}}